Effect of Zhuxiang Powder combined with novel dressing on healing of chronic wound
Objective To investigate the promotive effect of Zhuxiang Powder combined with novel dressing on healing of chronic wound(CW).Methods A total of 100 CW patients treated in our hospital from June 2021 to January 2023 were ran-domly assigned into treatment group(n =50)and control group(n =50).All patients were managed by routine Western medi-cine,and those in treatment group additionally received Zhuxiang Powder combined with novel dressing.Treated for 1 month,the aim was to compare visual analogue scale(VAS)for pain,inflammatory factors including interleukin-6(IL-6)and tumor necrosis factor-alpha(TNF-α),hospitalization time,frequency of dressing changes,wound healing time,satisfaction.The curative effect and adverse reactions were assessed.Results The overall effective rate in the treatment group was better than that in the control group(96.00%[48/50]vs72.00%[36/50],[P<0.05],respectively).After treatment,the patients in the two groups presented significantly lower VAS score,decreased levels of IL-6,TNF-α(all P<0.05)than those before treat-ment,and the improvements were more pronounced in the treatment group than those of the control group(all P<0.05).Pa-tients in the observation group presented significantly shorter hospitalization time,frequency of dressing changes,wound healing time,significantly higher satisfaction than those of control group(P<0.05).The total incidence of adverse reactions in the treatment group was significantly lower than that in the control group(4.00%[2/50]vs 18.00%[9/50],[P<0.05],re-spectively).Conclusion For CW patients,Zhuxiang Powder combined with novel dressing has definite curative effect,which can effectively reduce pain symptoms,reduce IL-6 and TNF-α levels,inhibit inflammatory response,thereby shortening hospitali-zation time and wound healing time,reducing frequency of dress-ing changes,improving satisfaction,and it is safe and reliable.
Wounds and injuriesWound healingDressingTraditional Chinese medicine therapy
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NSTL
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