Objective To investigate the promotive effect of Zhuxiang Powder combined with novel dressing on healing of chronic wound(CW).Methods A total of 100 CW patients treated in our hospital from June 2021 to January 2023 were ran-domly assigned into treatment group(n =50)and control group(n =50).All patients were managed by routine Western medi-cine,and those in treatment group additionally received Zhuxiang Powder combined with novel dressing.Treated for 1 month,the aim was to compare visual analogue scale(VAS)for pain,inflammatory factors including interleukin-6(IL-6)and tumor necrosis factor-alpha(TNF-α),hospitalization time,frequency of dressing changes,wound healing time,satisfaction.The curative effect and adverse reactions were assessed.Results The overall effective rate in the treatment group was better than that in the control group(96.00%[48/50]vs72.00%[36/50],[P<0.05],respectively).After treatment,the patients in the two groups presented significantly lower VAS score,decreased levels of IL-6,TNF-α(all P<0.05)than those before treat-ment,and the improvements were more pronounced in the treatment group than those of the control group(all P<0.05).Pa-tients in the observation group presented significantly shorter hospitalization time,frequency of dressing changes,wound healing time,significantly higher satisfaction than those of control group(P<0.05).The total incidence of adverse reactions in the treatment group was significantly lower than that in the control group(4.00%[2/50]vs 18.00%[9/50],[P<0.05],re-spectively).Conclusion For CW patients,Zhuxiang Powder combined with novel dressing has definite curative effect,which can effectively reduce pain symptoms,reduce IL-6 and TNF-α levels,inhibit inflammatory response,thereby shortening hospitali-zation time and wound healing time,reducing frequency of dress-ing changes,improving satisfaction,and it is safe and reliable.
Wounds and injuriesWound healingDressingTraditional Chinese medicine therapy
NETL
NSTL
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