首页|五禽戏鸟戏联合基于中医辨证的中医适宜技术对非小细胞肺癌化疗患者胃肠道及免疫功能的影响

五禽戏鸟戏联合基于中医辨证的中医适宜技术对非小细胞肺癌化疗患者胃肠道及免疫功能的影响

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目的 观察五禽戏鸟戏联合基于中医辨证的中医适宜技术对非小细胞肺癌(NSCLC)化疗患者胃肠道及免疫功能的影响.方法 将100 例NSCLC化疗患者按照随机数字表法分为2 组,对照组50 例予常规干预,研究组50 例在对照组基础上予五禽戏鸟戏联合基于中医辨证的中医适宜技术干预.2 组均干预1 个月.比较2 组干预前后CD4+、CD8+、CD4+/CD8+、症状评分、6 min步行距离(6-MWT)、抑郁自评量表(SDS)、焦虑自评量表(SAS)评分及干预后胃肠道反应发生率.结果 研究组干预后CD4+、CD4+/CD8+均较本组干预前升高(P<0.05),CD8+均降低(P<0.05),对照组干预后CD4+、CD8+、CD4+/CD8+均降低(P<0.05),且研究组干预后CD4+、CD4+/CD8+均高于对照组(P<0.05),CD8+低于对照组(P<0.05).研究组干预后胃肠道反应发生率 6.00%(3/50),对照组胃肠道反应发生率为24.00%(12/50),研究组干预后胃肠道反应发生率低于对照组(P<0.05).2 组干预后各项症状评分均较本组干预前降低(P<0.05),且研究组干预后均低于对照组(P<0.05).2 组干预后6-MWT均较本组干预前升高(P<0.05),且研究组干预后高于对照组(P<0.05).2 组干预后SAS、SDS评分均较本组干预前降低(P<0.05),且研究组干预后低于对照组(P<0.05).结论 五禽戏鸟戏联合基于中医辨证的中医适宜技术能够提高NSCLC化疗患者的免疫功能和运动耐力,降低患者的胃肠道反应,改善NSCLC化疗患者的症状和心理状况.
Effect of Wuqinxi bird exercises combined with traditional Chinese medicine appropriate techniques on gastrointestinal and immune functions of chemotherapy patients with non-small cell lung cancer:Based on syndrome identification
Objective To study the effects of the combination of Wuqinxi bird exercises and traditional Chinese medi-cine(TCM)appropriate techniques based on syndrome identification on the gastrointestinal and immune functions of non-small cell lung cancer(NSCLC)patients undergoing chemotherapy.Methods A total of 100 NSCLC chemotherapy patients were ran-domly divided into control group and study group.All patients received routine intervention,those in study group additionally re-ceived Wuqinxi bird exercises plus TCM appropriate techniques based on syndrome identification.Both groups were intervened for one month,aiming to compare the immune function indicators such as CD4+,CD8+,CD4+/CD8+,scores of TCM syndrome,six-minute walking test(6-MWT),self-rating anxiety scale(SAS),self-rating depression scale(SDS),and the inci-dence of gastrointestinal reactions between groups.Results After intervention,the levels of CD4+and CD4+/CD8+in the study group were significantly increased(P<0.05),while CD8+levels were significantly decreased(P<0.05).The levels of CD4+,CD8+and CD4+/CD8+in the control group after intervention were significantly decreased(P<0.05).The study group was superior to the control group for the levels of CD4+,CD8+and CD4+/CD8+(all P<0.05).After intervention,the inci-dence of gastrointestinal reactions in the study group was significantly lower than that of the control group(6%[3/50]vs 24%[12/50],P<0.05).The scores of TCM syndromes in the two groups were significantly lower than those before intervention(P<0.05),and the decreases were more pronounced in the study group relative to the control group(P<0.05).After inter-vention,significantly increased 6-MWT score,and significantly decreased scores of SAS and SDS were found in the two groups(all P<0.05),and the study group was superior to the control group for scores of 6-MWT,SAS and SDS(all P<0.05).Conclusion The combination of Wuqinxi bird exercises and TCM appropriate techniques based on syndrome identification can improve the immune function and exercise endurance in NSCLC chemotherapy patients,reduce gastrointestinal reactions,and improve their TCM symptoms and psychological status.It is worthy of clinical promotion.

Non-small cell lung cancerGastrointestinal reactionsImmune functionWuqinxi bird exercisesTradi-tional Chinese medicine appropriate techniques

于建平、刘戴维、耿艳琴

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河北北方学院附属第一医院中医科,河北 张家口 075000

非小细胞肺癌 胃肠道反应 免疫功能 五禽戏鸟戏 中医适宜技术

河北省张家口市重大科技计划

2021127H

2024

河北中医
河北省医学情报研究所,河北省中医药学会

河北中医

CSTPCD
影响因子:0.951
ISSN:1002-2619
年,卷(期):2024.46(5)