Effectiveness of herbal medicine sealing therapy combined with bundle infection management in reducing the risk of nos-ocomial pulmonary infection
Objective To observe the effectiveness of herbal medicine sealing therapy combined with bundle infection management in reducing the risk of nosocomial pulmonary infection(NPI).Methods A total of 150 patients receiving mechani-cal ventilation admitted to intensive care unit(ICU)were randomly assigned into control group(n=75)and intervention group(n=75).All patients were managed by routine infection management schemes,and those in intervention group additionally re-ceived herbal medicine sealing therapy combined with bundle infection management.The intervention continued until the transfer out of ICU.The aim was to compare pulmonary infection rate,28-day mortality,mechanical ventilation duration,ICU hospitali-zation time,clinical pulmonary infection score(CPIS),CURB-65(confusion,uremia,respiratory rate,blood pressure,age 65 years)score,quality rate of surface disinfection of high-frequency objects,numbers of air bacteria at hours 0 and 5 of disin-fection,cognitive level of environmental cleaning in cleaning staff between groups.Results Patients in the intervention group presented significantly lower pulmonary infection rate,28-day mortality,mechanical ventilation duration,and ICU hospitaliza-tion time(P<0.05).Patients in the intervention group had significantly lower CPIS and CURB-65 scores,significantly higher quality rate of surface disinfection of high-frequency objects,significantly lower numbers of air bacteria at hours 0 and 5 of dis-infection(P<0.05).The cognitive level of environmental cleaning in cleaning staff were significantly higher than those of control group(P<0.05).Conclusion The herbal medicine sealing therapy combined with infection management bundle can improve the quality of environmental cleaning,reduce the risk and severity of NPI,and improve cognitive level of environmental cleaning in cleaning staff.
InfectionLungChinese medicine therapyOrganization and managementCross infection
NETL
NSTL
万方数据
