Clinical study on the application of Jianpi Huatan Formula in improving gastrointestinal adverse reactions and nutri-tional status in chemotherapy patients with lung cancer
Objective To study the clinical effect of Jianpi Huatan Formula in improving gastrointestinal adverse reac-tions and nutritional status in chemotherapy patients with lung cancer.Methods Eighty-six chemotherapy patients with lung cancer admitted to Department of Oncology,Qinhuai Medical Area,General Hospital of Eastern Theater Command from January 2021 to December 2022 were randomly divided into a control group(n=43)and a study group(n=43).All patients received routine nursing intervention,those in the study group additionally received Jianpi Huatan Formula.The traditional Chinese medi-cine(TCM)symptom score,gastrointestinal adverse reactions,nutritional status,cancer-related fatigue,and immune function were compared between groups.Results Before intervention,there was no statistically significant difference in TCM syndrome scores,Patient-Generated Subjective Global Assessment(PG-SGA)scores,serum albumin(ALB),hemoglobin(Hb)lev-els,immunoglobulin G(IgG),immunoglobulin M(IgM),immunoglobulin A(IgA)levels,and Revised Piper Fatigue Scale(RPFS)scores between groups(P>0.05).After intervention,the TCM syndromes scores,incidence of gastrointestinal adverse reactions,and RPFS scores in the study group were significantly lower than those of the control group(P<0.05).After inter-vention,the PG-SGA score of the study group was significantly lower than that of the control group,while the levels of ALB and Hb were significantly higher(P<0.05).After intervention,the levels of IgG,IgM,and IgA in the study group were significant-ly higher than those of the control group(P<0.05).Conclusion The application of Jianpi Huatan Formula in chemotherapy patients with lung cancer can effectively improve their clinical symptoms,nutritional status,and cancer-related fatigue,reduce gastrointestinal adverse reactions,and improve their immune function,which is worthy of clinical promotion.
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