Clinical efficacy of Yishen Jiejing Decoction combined with acupuncture for post-stroke shoulder-hand syndrome
Objective To observe the clinical efficacy of Yishen Jiejing Decoction combined with acupuncture for post-stroke shoulder-hand syndrome(PS-SHS).Methods A total of 120 PS-SHS patients between December 2019 and Decem-ber 2021 were selected.They were randomly assigned to receive routine Western medicine(RWM)+Yishen Jiejing Decoction(Chinese medicine group,n=40),RWM+acupuncture(acupuncture group,n=40),or RWM+Yishen Jiejing Decoction+acupuncture(combination group,n=40).Treated for 4 weeks,the aim was to compare the shoulder range of mo-tion(ROM)(including lifting and abduction),shoulder-hand syndrome scale(SHSS)score,visual analogue scale(VAS)score,substance P(SP),bradykinin(BK),T lymphocyte subsets CD3+,CD4+,CD8+,compound muscle action potential(CMAP)amplitudes and conduction velocity of ulnar nerve and median nerve on day 0 and at weeks 2 and 4.The curative effect was assessed.Results The overall effective rate in the combination group was better than that in the Chinese medicine group and the acupuncture group(97.50%[39/40]vs 82.50%[33/40]vs 80.00%[32/40],[P<0.05],respectively).The shoulder ROM(including lifting and abduction)at weeks 2 and 4 in the three groups was significantly increased than that on day 0,but SHSS and VAS scores were significantly decreased(all P<0.05),and the combination group was superior to the Chinese medicine group and the acupuncture group for shoulder ROM,SHSS and VAS scores at weeks 2 and 4(all P<0.05).The ser-um SP and BK at weeks 2 and 4 in the three groups were significantly decreased than those on day 0(P<0.05),which were significantly lower in the combination group than in the Chinese medicine group and the acupuncture group(P<0.05).The lev-els of T lymphocyte subsets CD3+,CD4+,CD8+in the three groups at weeks 2 and 4 were comparable to those on day 0(P>0.05).Conclusion Yishen Jiejing Decoction combined with acupuncture has definite clinical efficacy in PS-SHS,and which can effectively improve clinical symptoms,promote nerve repair,and promote limb function recovery by lowering SP and BK levels.
StrokeShoulder-hand syndromeTraditional Chinese medicine therapyAcupuncture therapy
NETL
NSTL
万方数据
