Correlation between 25-hydroxyvitamin D and pulse wave velocity in H-type hypertension of different TCM syn-dromes
Objective To study the correlation between 25-hydroxyvitamin D(25(OH)D)and pulse wave velocity(PWV)in H-type hypertension patients with different traditional Chinese medicine(TCM)syndromes.Methods Totally 100 patients with H-type hypertension in Xinyu People's Hospital from December 2021 to September 2022 were recruited,they were divide into excessive phlegm and dampness group(group A),deficiency of both yin and yang group(group B),liver-fire hy-peractivity group(group C),and asthenic yin causing predominant yang group(group D)according to different TCM syn-dromes.The general data including age,gender,past history were collected.The blood glucose,blood lipid,serum homocys-teine(Hcy),25(OH)D,PWV were measured.The correlation between25(OH)D and PWV was analyzed.Results The aver-age systolic blood pressure(SBP)and diastolic blood pressure(DBP)of the four groups were(155.61±10.61)mmHg and(87.91±11.15)mmHg,respectively,and with no statistically significant difference in blood pressure(P>0.05).The serum Hcy levels were significantly higher in group A and group B than in group C and group D(P<0.05),and with no significant differences in other pairwise comparisons(P>0.05).There were no significant differences in PWV,25(OH)D,fasting blood glu-cose,blood lipid among the four groups(all P>0.05).The PWV of group A and group B was negatively correlated with25(OH)D level(P<0.05).The PWV of group C and group D was negatively correlated with25(OH)D level,but the correlation was not statistically significant(P>0.05).Conclusion Vitamin D is deficient in H-type hypertension patients with excessive phlegm and dampness or deficiency of both yin and yang.It is necessary to correct it in time to reduce PWV,improve vascular elasticity,delay atherosclerosis,and thus reduce the occurrence of stroke.
H-type hypertensionTraditional Chinese medicine syndromes25-hydroxyvitamin DPulse wave velocityCorrelation
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