Study on the protective effect of Chinese medicine compatibility containing curcumin on renal function in type 2 diabetes nephropathy
Objective To observe the protective effect of Chinese medicine compatibility containing curcumin on renal function in type 2 diabetes nephropathy(T2DN).Methods Seventy patients with type 2 diabetes were randomly divided into treatment group and control group,35 cases in each group.Control group was treated with losartan potassium tablets,while treatment group was treated with Chinese medicine compatibility containing curcumin on the basis of control group.The therapeutic effects,the levels of total cholesterol(TC),triglycerides(TG),urinary microalbumin(U-mAlb),serum creatinine(Scr),24-hour urine protein,homocysteine(Hcy),fasting blood glucose(FPG),postprandial 2-hour blood glucose(2 hPG),hypersensitive C-reactive protein(hs-CRP),and white blood cell count(WBC)of the two groups were compared.Results After treatment,the total effective rate of treatment group was higher than that of control group(P＜0.05);TC,TG,U-mAlb,Scr,24-hour urine protein,Hcy,FPG,2 hPG,hs-CRP,and WBC were lower than before treatment,and were lower in treatment group than control group(P＜0.05).Conclusion Chinese medicine compatibility containing curcumin has a significant protective effect on the renal function of T2DN,significantly reducing blood lipids and blood sugar,improving renal function,and regulating micro inflammatory state.
Type 2 diabetesKidney diseaseRenal functionCurcuminChinese medicine compatibility
万方数据
维普
