Podocyte injury is an important cause of diabetes nephropathy(DN),and DN is the main cause of end-stage renal disease.At present,the research on the mechanism of podocyte injury has made some progress,but there is still a lack of specific treatment in clinic,which is difficult to cure.SIRT1,AMPK and mTOR have different degrees of changes in diabetes nephropathy,and the change mechanism may be synergistic or antagonistic.This paper discusses the possibility and mechanism of acupuncture in preventing and treating DN by sorting out the research on the mechanism of acupuncture on the three pathways in recent years,so that acupuncture can better serve the clinic and further develop the research on acupuncture.
维普
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