湖北中医药大学学报2024,Vol.26Issue(1) :125-129.DOI:10.3969/j.issn.1008-987x.2024.01.34

止嗽散治疗呼吸系统疾病的药理作用及其临床应用进展

The pharmacological action and clinical application of Zhisou Powder in respiratory diseases

郑晨 骆天炯
湖北中医药大学学报2024,Vol.26Issue(1) :125-129.DOI:10.3969/j.issn.1008-987x.2024.01.34

止嗽散治疗呼吸系统疾病的药理作用及其临床应用进展

The pharmacological action and clinical application of Zhisou Powder in respiratory diseases

郑晨 1骆天炯2
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作者信息

  • 1. 南京中医药大学,江苏南京 210023
  • 2. 南京中医药大学附属南京中医院老年科,江苏南京 210023
  • 折叠

摘要

止嗽散载于《医学心悟》,全方温润平和,不寒不热,可宣利肺气,止咳化痰,在喘、咳嗽、虚劳、伤寒兼见症中均可使用,是治疗风邪犯肺型咳嗽的代表方.现代药理学研究该方具有改善气道炎症、减轻肺损伤、减轻气道重构等作用,多加减化裁用于各呼吸系统疾患引起的咳嗽,如急慢性支气管炎、感染后咳嗽、慢性咳嗽、变异性哮喘、儿童咳嗽、ACEI咳嗽等.本文基于TRP、NF-κB信号通道与咳嗽发生的关系,探讨止嗽散治疗呼吸系统疾患的药理作用及其临床应用.

Abstract

Zhisou Powder is recorded in Medical Insight,the whole prescription is moderate.It can be used in wheezing,cough,exhaustion,typhoid syndrome.It has the effect of promoting lung qi,relieving cough and eliminating phlegm.Modern pharmacological studies show that this prescription can reduce airway inflammation,enhance immunity,alleviate lung injury.It is used for cough caused by various respiratory system diseases.Such as acute and chronic bronchitis,cough after infection,chronic cough,variant asthma,children's cough,ACEI cough and other respiratory diseases.We elaborate the relationship between TRP,NF-κB signal channel and cough to discuss the possible mechanism of Zhisou Powder and its clinical application in respiratory diseases.

关键词

止嗽散/TRP信号通道/NF-κB信号通道/药理作用/呼吸系统疾病/临床应用

Key words

Zhisou Powder/TRP signal pathway/NF-κB signal pathway/Pharmacological action/Respiratory diseases/Clinical application

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基金项目

江苏省老年健康科研项目(LD2021026LR2021039)

出版年

2024
湖北中医药大学学报
湖北中医药大学

湖北中医药大学学报

CSTPCD
影响因子:0.873
ISSN:1008-987X
被引量1
参考文献量40
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