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中药口服联合穴位贴敷治疗小儿重症肺炎疗效研究

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目的 观察中药口服联合穴位贴敷治疗小儿重症肺炎临床疗效.方法 将我院90例重症肺炎患儿随机为治疗组与对照组各45例.对照组行美罗培南+布地奈德混悬液治疗,治疗组在上述治疗基础上行中药口服联合穴位贴敷治疗.比较两组总好转率,治疗前后动脉血氧分压(PaO2)、动脉血二氧化碳分压(PaCO2)、氧合指数(Oi),第1秒用力肺活量(FEV1)、用力肺活量(FVC)、FEV1/FVC,C反应蛋白(CRP)、降钙素原(PCT)、白细胞计数(WBC),退热、咳嗽消失和肺啰音消失时间及治疗前后临床肺部感染评分(CPIS).结果 治疗后,治疗组总有效率显著高于对照组(P<0.05);两组PaO2、Oi高于治疗前,PaCO2低于治疗前,治疗组PaO2、Oi高于对照组,PaCO2低于对照组(P<0.05);两组FEV1、FVC、FEV1/FVC高于治疗前,治疗组FEV1、FVC、FEV1/FVC高于对照组(P<0.05);两组CRP、PCT、WBC低于治疗前,治疗组CRP、PCT、WBC低于对照组(P<0.05);治疗组退热、咳嗽消失和肺啰音消失时间均少于对照组(P<0.05);两组CPIS低于治疗前,治疗组CPIS低于对照组(P<0.05).结论 中药口服联合穴位贴敷治疗小儿重症肺炎疗效较好,可改善缺氧和呼吸衰竭,提高肺功能,降低炎性反应,缩短病程,缓解病情.
Efficacy observation on oral administration of TCM combined with acupoint application in treatment of severe pneumonia in children
Objective To observe the therapeutic effect of oral administration of TCM and acupoint application in treatment of severe pneumonia in children.Methods Ninety children with severe pneumonia were randomly divided into treatment group and control group,with 45 cases in each group.Control group was treated with meropenem+budesonide suspension,while treatment group was treated with oral administration of TCM combined with acupoint application on the basis of control group.The total improvement rate,arterial partial pressure of oxygen(PaO2),partial pressure of arterial carbon dioxide(PaCO2),oxygenation index(Oi),forced vital capacity at 1 second(FEV1),forced vital capacity(FVC),FEV1/FVC,C-reactive protein(CRP),procalcitonin(PCT),white blood cell count(WBC)and depyretic,disappearance of cough and pulmonary rales before and after treatment,and clinical pulmonary infection score(CPIS)before and after treatment were compared between the two groups.Results After treatment,the total effective rate of treatment group was significantly higher than control group(P<0.05),and the levels of PaO2 and Oi of both groups were higher than those before treatment,which were higher in treatment group than control group,while PaCO2 was lower in both groups than before treatment,which was lower in control group than treatment group(P<0.05);FEV1,FVC and FEV1/FVC in both groups were higher than before treatment,which were higher in treatment group than control group(P<0.05);the CRP,PCT and WBC in both groups were lower than before treatment,which were lower in treatment group than control group(P<0.05);the time of fever reduction,cough disappearance and pulmonary rales disappearance in treatment group was lower than control group(P<0.05);the CPIS of both groups was lower than that before treatment,which was lower in treatment group than control group(P<0.05).Conclusion The oral administration of TCM combined with acupoint application has a good effect in treatment of severe pneumonia in children,which can improve hypoxia and respiratory failure,improve lung function,reduce inflammation,shorten the disease course of the disease,and alleviate the patients'condition.

Severe pneumoniaChildOral administration of TCMAcupuncture point application

闫春梅、袁小霞

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陕西省榆林市中医医院儿科,陕西榆林 719000

重症肺炎 小儿 中药口服 穴位贴敷

陕西省社会发展项目

2019SF-064

2024

湖北中医药大学学报
湖北中医药大学

湖北中医药大学学报

CSTPCD
影响因子:0.873
ISSN:1008-987X
年,卷(期):2024.26(2)
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