Therapeutic effect of Simo Decoction combined with Jin Shuangqi Tablets on functional dyspepsia in children
Objective To observe the clinical efficacy of Simo Decoction combined with Jin Shuangqi Tablets in the treatment of functional dyspepsia(FD)in children.Methods Ninety-six children with FD were randomly divided into treatment group and control group,with 48 cases in each group.Control group was given Jin Shuangqi Tablets,and treatment group was given Simo Decoction on the basis of control group.The clinical efficacy,recurrence rate,incidence of adverse reactions,disappearance time of belching and epigastric discomfort,residual antral amount at 60,90 and 120 min,the recurrence rate,incidence rate of adverse reactions,disappearance time of belching and epigastric discomfort,body mass index(BMI),and TCM syndrome scores in 6-month follow-up were compared between the two groups.Results After treatment,the total effective rate of treatment group was significantly higher than control group(P＜0.05);the recurrence rate of treatment group was significantly lower than control group in 6-month follow-up(P＜0.05);and there was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05);the disappearance time of belching was shorter and epigastric discomfort was less in treatment group than control group(P＜0.05);the antral residue and TCM pattern score at 60,90 and 120 min after eating in both groups were lower than those before treatment,and were lower in treatment group than control group(P＜0.05);the BMI of both groups was higher than that before treatment,which was higher in treatment group than control group(P＜0.05).Conclusion The combination of Simo Decoction and Jin Shuangqi Tablets significantly improves the therapeutic effect of pediatric FD,reduces the recurrence rate and incidence of adverse reactions,enhances gastric emptying,promots growth and development,and relieves TCM syndromes.
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