Therapeutic effect of Xiangsha Liujun Pills on postoperative spleen deficiency and dampness obstruction syndrome in colorectal cancer patients
Objective To observe the therapeutic effect of Xiangsha Liujun Pills on postoperative spleen deficiency and dampness obstruction syndrome in colorectal cancer.Methods Sixty-eight postoperative patients with colorectal cancer were randomly divided into treatment group and control group,with 34 cases in each group.Control group received chemotherapy treatment,while treatment group received Xiangsha Liujun Pills on the basis of control group.The body mass,quality of life,and therapeutic effects of TCM syndromes were compared between the two groups;the time of appearance of intestinal sounds,initial exhaust time,and initial defecation time were recorded and compared between the two groups;the levels of carcinoembryonic antigen(CEA),carbohydrate antigen(CA)19-9,T lymphocyte subsets(CD3+,CD4+),and natural killer cells(NK)were detected and compared between the two groups.Results After treatment,the improvement rates of body weight,quality of life and TCM syndrome in treatment group were higher than control group(P＜0.05);the time of intestinal sounds,first discharge and first defecation in treatment group were significantly shorter than control group(P＜0.05);there was no significant difference in CEA and CA19-9 between the two groups(P＞0.05);CD3+,CD4+and NK in treatment group were higher than those before treatment,and were higher than control group,CD3+,CD4+and NK were lower in control group than before treatment(P＜0.05).Conclusion Xiangsha Liujun Pills have a good effect on spleen deficiency and dampness obstruction syndrome after colorectal cancer surgery,which can improve patients'body weight,quality of life,TCM syndrome,restore gastrointestinal function,and improve immunity,but has little effect on tumor markers.
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