Application of in situ detection of exosomal non-coding RNAs in tumor diagnosis and TCM Research
Exosomal non-coding RNAs(EXO-NCRNAs)are dysregulated in various types of tumors and have a clear correlation with tumor occurrence and development,making them potential liquid biopsy biomarkers for tumors.In recent years,many traditional Chinese medicines,including monomers,formulations,have been found to play anti-tumor roles by regulating the expression of EXO-NCRNAs,suggesting that exosomes have the potential to become new targets for tumor treatment,and the detection of EXO-NCRNAs can contribute to the evaluation of the therapeutic efficacy and the mechanistic research of traditional Chinese medicine components in anti-tumor treatment.This review summarized the traditional detection methods and new biosensing strategies for EXO-NCRNAs,introduced the research progress on its application in tumor diagnosis,and discussed the potential prospects of their application in traditional Chinese medicine.
ExosomeNon-coding RNAsIn situ detectionTumor diagnosisTraditional Chinese medicine
NETL
NSTL
万方数据
