首页|白藜芦醇治疗帕金森病的研究进展

白藜芦醇治疗帕金森病的研究进展

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帕金森病(PD)是一种老年神经退行性疾病,由于左旋多巴"替代疗法"的治疗有限,因此,积极寻找多靶点且安全有效的药物对PD的预防和治疗更具意义.白藜芦醇作为从植物中分离的一种天然多酚,已被证实具有极强的神经保护作用,其通过多种途径如抗氧化、抗炎、保护线粒体等方面,防治包括PD在内的许多神经系统疾病.本文综述白藜芦醇针对PD发病机制所发挥的潜在神经保护作用,以期对临床应用白藜芦醇防治PD提供理论参考.
Research progress of resveratrol in treating Parkinson's disease
Parkinson's disease(PD)is a neurodegenerative disease in the elderly.Due to the limited therapeutic effect of levodopa"replacement therapy",it is more meaningful to actively search for multi-target,safe and effective drugs for the prevention and treatment of PD.As a natural polyphenol isolated from plants,resveratrol has been confirmed to have strong neuroprotective effects.It can prevent and treat many nervous system diseases including PD through a variety of pathways such as anti-oxidation,anti-inflammation,and mitochondrial protection.This article reviews the potential neuroprotective effects of resveratrol on the pathogenesis of PD,in order to provide theoretical reference for the clinical application of resveratrol in the prevention and treatment of PD.

ResveratrolParkinson's diseaseNeurodegenerative diseases

李媛媛、包小立、汪瑶、王彦春

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湖北中医药大学针灸骨伤学院,湖北武汉 430065

湖北中医药大学中医临床学院,湖北武汉 430065

白藜芦醇 帕金森病 神经退行性疾病

国家自然科学基金项目教育部"新世纪优秀人才支持计划"项目

30973809NCET-10-0154

2024

湖北中医药大学学报
湖北中医药大学

湖北中医药大学学报

CSTPCD
影响因子:0.873
ISSN:1008-987X
年,卷(期):2024.26(2)
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