Clinical observation on Tanreqing Injection combined with cefoperazone/sulbactam sodium in treatment of bronchiectasis with pulmonary infection
Objective To observe the clinical efficacy of cefoperazone/sulbactam sodium combined with Tanreqing Injection in treatment of bronchiectasis with pulmonary infection(BCPI).Methods 89 patients with BCPI were randomly divided into control group(45 cases)and treatment group(44 cases).Control group was treated with cefoperazone/sulbactam sodium,and treatment group was treated with Tanreqing Injection on the basis of control group.The clinical efficacy of the two groups was compared;the levels of white blood cell count(WBC),procalcitonin(PCT),C-reactive protein(CRP)and neutrophil percentage(NEU％)were observed,the TCM symptom score was evaluated,the forced expiratory volume in one second(FEV1)and forced vital capacity(FVC)were measured,and the St.George's Respiratory Questionnaire(SGRQ)scores of the were compared.Results After treatment,the total effective rate of treatment group was higher than that of control group(P＜0.05);WBC,PCT,CRP,NEU％levels in both groups were lower than those before treatment,and were lower in treatment group than control group(P＜0.05);the TCM symptom scores of both groups were lower than those before treatment,and were lower in treatment group than control group(P＜0.05);FEV1 and FVC in both groups were higher than those before treatment,and were higher in treatment group than control group(P＜0.05);the SGRQ scores of both groups were lower than those before treatment,and were lower in treatment group than the control group(P＜0.05).Conclusion Cefoperazone/sulbactam sodium combined with Tanreqing Injection can reduce infection,improve symptoms,improve lung function and improve clinical efficacy in treatment of BCP1.
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