Curative effect observation on Guizhi Fuling Capsules combined with mifepri-stone in treatment of uterine fibroids
Objective To observe the clinical therapeutic effect of Guizhi Fuling Capsules combined with mifepristone in treatment of uterine fibroids.Methods 80 patients with uterine fibroids were randomly divided into control group and treatment group,with 40 cases in each group.Control group was treated with mifepristone,and treatment group was treated with Guizhi Fuling Capsules on the basis of control group.The total effective rate,luteinizing hormone(LH),estradiol(E2),follicle-stimulating hormone(FSH)and progesterone(P)levels were measured,uterus volume and fibroids volume were measured,the menstrual flow and menstrual time were compared,and the scores of major and minor symptoms were quantitatively of the two groups were compared.Results After treatment,the total effective rate of treatment group was higher than control group,LH,E2,FSH,P scores,uterine volume,fibroid volume,menstrual flow,menstrual duration,major and minor symptom scores in both groups were lower than those before treatment,and were lower in treatment group than control group(P＜0.05).Conclusion Guizhi Fuling Capsules combined with mifepristone has good curative effects in treatment of uterine fibroids,improving sex hormone level,shrinking the size of uterus and fibroids,regulating menstrual period and menstrual time,and alleviating major and secondary symptoms.
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