Clinical study on Gegen Decoction and Tianma Gouteng Decoction in treatment of spastic hemiplegia after stroke
Objective To observe the clinical effect of Gegen Decoction combined with Tianma Gouteng Decoction on spastic hemiplegia(SPAS)after stroke.Methods A total of 120 patients with SPAS were randomly divided into control group and experimental group with 60 cases in each group.Control group received routine neurological treatment combined with re-habilitation training,and experimental group was treated with Gegen Decoction and Tianma Gouteng Decoction on the basis of control group.The clinical efficacy,quality of life,coagulation indexes and dynamic changes of electromyography were compared between the two groups.Results After treatment,the clinical efficacy of experimental group was significantly higher than that of control group(P<0.05);the scores of each dimension of SF-36 in both groups were significantly higher than those before treatment,the scores of SF-36 dimensions in experimental group were significantly higher than those in control group(P<0.05);the prothrombin time(PT),thrombin time(TT),and activated partial thromboplastin time(APTT)in both groups were significantly higher than those before treatment,while the FBG level was significantly lower than that before treatment,the PT,TT,and APTT in experimental group were significantly higher than those in control group,while the fibrinogen(FBG)level was significantly lower(P<0.05);the motor nerve conduction velocity(MCV)and motor potential amplitude(MPA)of the median nerve,radial nerve,and ulnar nerve in both groups were significantly higher than those before treatment,and the motor potential latency(MPL)was significantly lower than that before treatment,and the above indexes were superior in observation group to those in control group(P<0.05).Conclusion Gegen Decoction combined with Tianma Gouteng Decoction is effective in SPAS,which is helpful to improve the quality of life,improve coagulation index and promote the recovery of neurological function.
StrokeSpastic hemiplegiaGegen Decoction combined with Tianma Gouteng DecoctionQuality of lifeElec-tromyogram