摘要
目的 观察艾迪注射液联合全程肺康复训练对肺癌根治术患者肺功能及体力活动的影响.方法 将我院100例肺癌根治术患者随机分为对照组与观察组各50例.对照组实施全程肺康复训练方案,观察组在对照组的治疗基础上采用艾迪注射液.比较两组总有效率及自然杀伤细胞(NK)、CD3+、CD4+、CD8+百分比;两组免疫球蛋白(IgA、IgG、IgM),1秒率(FEV1/FVC)、肺活量(VC)、肺一氧化碳弥散量(DLCO)和肺癌生存质量评定量表、简易咳嗽程度量表(CET)、肌力分级(MRC)评分.结果 治疗后,观察组总有效率高于对照组(P＜0.05);两组NK、CD3+、CD4+百分比高于治疗前,CD8+百分比低于治疗前,观察组NK、CD3+、CD4+百分比高于对照组,CD8+百分比低于对照组(P＜0.05);两组IgA、IgG、IgM水平高于治疗前,观察组IgA、IgG、IgM水平高于对照组(P＜0.05);两组FEV1/FVC、VC、DLCO高于治疗前,观察组FEV1/FVC、VC、DLCO高于对照组(P＜0.05);两组肺癌生存质量评定量表评分高于治疗前,观察组肺癌生存质量评定量表高于对照组(P＜0.05);两组CET评分低于治疗前,MRC评分高于治疗前,观察组CET评分低于对照组,MRC评分高于对照组(P＜0.05).结论 艾迪注射液联合全程肺康复训练对肺癌根治术患者有较好的疗效,调节免疫功能,改善生存质量,提高肺功能和体力,减轻咳嗽.
Abstract
Objective To observe the effect of Eddy Injection combined with pulmonary rehabilitation training on lung function and physical activity in patients undergoing radical lung cancer resection.Methods A total of 100 patients undergoing radical lung cancer resection were randomly divided into control group and observation group,with 50 cases in each group.Control group was given a full pulmonary rehabilitation training program,and observation group was treated with Eddy Injection on the basis of control group.The total effective rate,the percentages of natural killer cells(NK),CD3+,CD4+,CD8+,immunoglobulins(IgA,IgG,IgM),1-second rate(FEV1/FVC),lung capacity(VC),diffusing capacity of carbon monoxide(DLCO),lung cancer quality of life rating scale,simple cough degree scale(CET)and muscle strength rating(MRC)scores of the two groups were analyzed.Results After treatment,the total effective rate of observation group was higher than that of control group(P＜0.05);the percentages of NK,CD3+and CD4+in both groups were higher than those before treatment,while the percentage of CD8+were lower,and the above indicators were superior in observation group to those in control group(P＜0.05);the levels of IgA,IgG and IgM in both groups were higher than those before treatment,and were higher in observation group than control group(P＜0.05);the levels of FEV1/FVC,VC and DLCO in both groups were higher than those before treatment,and were higher in observation group than control group(P＜0.05);the quality of life rating scale of lung cancer in both groups was higher than that before treatment,and was higher in observation group than control group(P＜0.05);the CET score of both groups was lower than that before treatment,while the MRC score was higher,and the above indicators were superior in observation group to those in control group(P＜0.05).Conclusion Eddy Injection combined with pulmonary re-habilitation training has a good effect on patients undergoing radical lung cancer resection,regulating immune function,improving quality of life,improving lung function and physical activity,and reducing cough.
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