Clinical analysis on modified Simiao Yong'an Decoction combined with etocoxib in treatment of acute attack of gout caused by type 2 diabetes
Objective To observe the therapeutic effect of modified Simiao Yong'an Decoction combined with etocoxib on type 2 diabetes with acute gout attack(T2DMGAA).Methods Seventy-five T2DMGAA patients were randomly divided into study group of 38 cases and control group of 37 cases.Control group was treated with etoposide,while study group was treated with modified Simiao Yong'an Decoction on the basis of control group.The clinical efficacy,TCM syndrome scores,Visual Analogue Scale(VAS)score,uric acid(UA),fasting blood glucose(FPG),postprandial 2-hour blood glucose(2 hPG),glycated hemoglobin(HbA1c),and interleukin-6(IL-6),white blood cell count(WBC),erythrocyte sedimentation rate(ESR)levels and overall adverse reaction rates were compared between the two groups.Results After treatment,the total effective rate of study group was higher than that of control group(P＜0.05);TCM syndrome scores,VAS scores,UA,FPG,2 hPG,HbA1c,IL-6,WBC,and ESR levels in both groups were lower than before treatment,and were lower in study group than control group(P＜0.05);there was no statistically significant difference in the total adverse reaction rates between the two groups(P＞0.05).Conclusion Modified Simiao Yong'an Decoction combined with etoricoxib has a good curative effect on T2DMGAA,which can significantly improve symptoms and signs,regulate glucose metabolism,down-regulate UA and inflammatory factors levels,reduce pain,and does not increase the rate of adverse reactions.
Type 2 diabetesGoutAcute attacksModified Simiao Yong'an DecoctionEtocoxib
NETL
NSTL
万方数据
