Research progress on the mechanism of acupuncture in treatment of rheumatoid arthritis
Rheumatoid arthritis(RA)is an autoimmune disease characterized by persistent synovitis,cartilage injury,and systemic inflammation.Clinical studies indicated that acupuncture has a significant therapeutic effect on RA.This article makes a comprehensive analysis of the research on acupuncture intervention in RA in recent years.It expounds the mechanism of action from six aspects:cytokine,T lymphocyte,adenosine receptor,NF-κB mediated signaling pathway,neuroendocrine-immune network system,and miRNA to provide a new perspective and enlightenment for the further mechanism research of acupuncture intervention in RA.
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