Effect and safety analysis of TCM patch combined with doxycycline in treatment of mycoplasma pneumonia
Objective To observe the efficacy and analysis the safety of TCM patch combined with doxycycline on my-coplasma pneumonia(MP).Methods A total of 96 children with MP were randomly divided into treatment group and control group,with 48 cases in each group.Control group was treated with doxycycline,while treatment group was treated with TCM patch on the basis of control group.The clinical efficacy,disappearance time of clinical symptoms,high-sensitivity C-reactive protein(hs-CRP),procalcitonin(PCT),D-dimer(D-D),TCM symptom score,and the incidence of adverse reactions were compared between the two groups.Results After treatment,the total effective rate of treatment group was higher than that of control group(P＜0.05);the disappearance time of clinical symptoms in treatment group was shorter than that of control group(P＜0.05);the symptoms of hs-CRP,PCT,D-D and TCM in both groups were lower than those before treatment,which were lower in treatment group than control group(P＜0.05),and the incidence of adverse reactions between the two groups was not statistically significant(P＞0.05).Conclusion TCM patch combined with doxycycline has better effects in treatment of MP,which can improve symptoms and signs,down-regulate inflammatory indexes,and improve coagulation function with a better safety profile.
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