The effect of Kangfuxin Liquid combined with periodontal basic treatment on severe invasive periodontitis
Objective To observe the effect of Kangfuxin Liquid combined with periodontal basic treatment on severe invasive periodontitis(SIP).Methods Seventy-six cases of SIP were randomly divided into control group and observation group,with 38 cases in each group.Control group received periodontal basic treatment,while observation group received Kangfuxin Liquid on the basis of control group.The cilinal efficacy,syndrome score,gingival bleeding index(SBI),probing depth(PD),clinical attachment level(CAL),plaque index(PLI),mobility(MD),sensory value,swelling,gingival crevicular fluid tumor necrosis factor-α(TNF-α),interleukin-1β(IL-1β),prostaglandin E2(PGE2),and matrix metalloproteinase-2(MMP-2)levels were compared between the two groups.Results After treatment,the total effective rate of observation group was higher than control group(P＜0.05);the syndrome scores were lower in both groups than before treatment,which were lower in observation group than control group(P＜0.05);the SBI,PD,CAL,PLI,MD,sensory values,swelling,and the levels of TNF-α,IL-1 β,PGE2,and MMP-2 in gingival crevicular fluid were all lower in both groups than before treatment,which were lower in observation group than control group(P＜0.05).Conclusion Kangfuxin Liquid combined with periodontal basic treatment significantly improves the efficacy of SIP patients by improving periodontal index,alleviating bad breath and swelling,and improving symptoms.
NETL
NSTL
万方数据
