The efficacy of modified Lianchen Decoction in treatment of Luoyu damp-resistant obesity complicated with hyperuricemia
Objective To observe the efficacy of modified Lianchen Decoction in treatment of Luoyu damp-resistant obesity complicated with hyperuricemia(OHU).Methods A total of 94 patients with depressed and damp-resistant OHU were randomly divided into control group and observation group,with 47 cases in each group.Control group was treated with lifestyle modification,while observation group was treated with modified Lianchen Decoction on the basis of control group.The body mass index(BMI),fat percentage,serum uric acid(UA),median arm of the lower edge of the right deltoid muscle(A),right inferior angle of scapula(B),3 cm next to the right umbilicus(C),subcutaneous fat thickness of the right anterior superior iliac spine(D),TCM symptom scores,triglycerides(TG),total cholesterol(TC),and low-density lipoprotein(LDL-C)were compared between the two groups.Results After treatment,the total effective rate of observation group was higher than that of control group(P＜0.05);BMI,fat percentage,and UA in both groups were lower than those before treatment,which were lower in observation group than control group(P＜0.05);the thickness of subcutaneous fat in both groups A～D was lower than that before treatment,which was lower in observation group than control group(P＜0.05);the TCM symptom scores in both groups were lower than those before treatment,which were lower in observation group than control group(P＜0.05);TC,TG,and LDL in both groups were lower than those before treatment,which were lower in observation group than control group(P＜0.05).Conclusion Modified Lianchen Decoction combined with lifestyle improvement has significant curative effects in treatment of Luoyu damp-resistant OHU,which can reduce BMI,UA,and subcutaneous fat thickness,improve clinical symptoms,and correct blood lipid disorders.
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