Progress in the application of modified Shuyu Pills in treatment of senile cognitive dysfunction
With the increasing aging of our population,the cognitive dysfunction associated with it has become a problem to be solved urgently.The modified Shuyu Pills,which was adapted from Synopsis of Golden Chamber,is a recipe for the pathogenesis of senile cognitive dysfunction,"spleen and kidney deficiency,phlegm and blood stasis interjunction".It has been used as a hospital preparation in the treatment of senile cognitive dysfunction for a long time with remarkable curative effect.This paper analyzed the related studies on modified Shuyu Pills,and summarized its mechanism of improving the cognitive function is to repair cholinergic system,inhibit neuroinflammation,regulate autophagy,improve synaptic plasticity,inhibit neuronal apoptosis,and promote myelin regeneration.