Selective Protection of 5'-Hydroxyl Group of Deoxynucleoside by Photosensitive Groups of Coumarin
In this paper,we utilized the photolabile coumarin compounds to replaced the acid remova-ble protective groups on the 5'-hydroxyl group on the deoxyriboside in nucleic acids'synthesis.The violent and blue light responsive coumarin segments were attached on the 5'-hydroxyl group on the N-4 acetyl deoxycytidine via the carbonate linker,and the synthesis photolysis was investigated under dif-ferent light irradiation.
photalabilecoumarindeoxynucleosidevisible light responsivephotosensitive unit syn-thesisDNA synthesis
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