Preparation of Size-controlled Organic Hybrid Silica Colloidal Particles
Organic hybrid silica colloidal particles are widely used in the field of biomedicine due to their unique properties.The size of nanoparticles required for different organs tissues is also different.Therefore,size-controllable organic hybrid silica colloidal particles play a crucial role in biomedical ap-plications.In this paper,vinyltrimethoxysilane(VTMS)was used as the precursor of silane,and am-monium hydroxide was used as the catalyst.Size-controlled organic hybrid silica colloidal particles were prepared by the spontaneous emulsification of the silane precursor under alkaline conditions,fol-lowed by polymerization initiated by ammonium persulfate(APS).The effects of different conditions,such as the type of initiator,precursor concentration,ammonium hydroxide concentration,and emulsi-fication time,on the size of the organic hybrid silica colloidal particles were investigated using field e-mission scanning electron microscopy and ImageJ software.The results showed that an increase in pre-cursor concentration led to an increase in the size of the organic hybrid silica colloidal particles,while an increase in ammonium hydroxide concentration had the opposite effect.
spontaneous emulsification of silanevinyltrimethoxysilaneammonium hydroxidesize-controlledorganic hybrid silica colloidal particle
万方数据
维普
