Fluorescent probe based on purine for detecting Zn2+and its application
A new"turn-on"fluorescent probe derived from purine-chromone Schiff base(E)-3-((2-(8,9-di(naphthalen-1-yl)-9H-purin-6-yl)hydrazono)methyl)-4H-chromen-4-one(DPHC)for detecting Zn2+was designed,synthesized and evaluated.The DPHC exhibited remarkable selectivity and rapid response towards Zn2+in DMSO/HEPES(v/v=9:1,pH=7.4),accompanying with a significant color change from colorless to pale green.A good linear relationship(R2=0.979 92)was obtained between the emission intensity of DPHC and the concentration of Zn2+(1-5 μmol/L)with low detection limit of 150.0 nmol/L.The sensing mechanism of DPHC to Zn2+was supported by the Job's plot and 1H-NMR.
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