The orthotropic steel deck of the upper flange of the steel box girder is prone to damage and crack un-der the repeated action of the vehicle wheel load,and more than 90%of the damage is fatigue damage,while the diaphragm is the main damage component of the orthotropic steel deck,accounting for 28.8%.In order to study the treatment method of orthotropic steel bridge deck floorbeam disease of steel box girder,through disease statis-tics,disease formation process tracking,disease cause analysis,and disease real bridge treatment,the orthotro-pic steel bridge deck floorbeam of steel box girder is described in detail.The treatment methods for four major types of floorbeam diseases are the base metal cracks at the arc cut of the plate,the base metal cracks at the welding holes on the floorbeam,the weld cracks between the floorbeam and the U-rib,and the weld cracks be-tween the floorbeam and the panel.According to the statistics of disease regeneration after three years of repair of Example Bridge 1,30 of the 480 floorbeam-related diseases repaired occurred,and the incidence of regeneration diseases was 6.25%;in the inspection three years later,the inspection after the completion of the reinforcement of the reinforced angle steel between the floorbeam of the bridge 3 and the U-rib welding seam showed that no re-generation diseases were found in the reinforcement part.The results show that the various disease maintenance methods described in this paper are reliable and have reference value for the same type of disease maintenance.