Accurate calculation of reactivity changes caused by impact is a key problem to be solved urgently in the design and safety analysis of micro-reactors.In this paper,neutron transport simulation and explicit finite element dynamics simulation based on unstructured-mesh Monte Carlo are combined to study the multi-physical coupling calculation of micro-reactor under the condition of large deformation of dynamic impact.Taking the 85-pin NaK-cooled space nuclear reactor as an example,the time-dependent variation of reactivity in the process of vertical and 45° dip impact is analyzed.The results show that,without considering the uniform density change of fluid and fuel,the keff caused by vertical impact increases by about 8%,while the keff caused by 45° impact increases by about 3%,which were in good agreement with the results in the literature.Under the condition of non-uniform fuel density change,the increase of keff in the two scenarios increased by about 10%and 20%,respectively.The research provides an important theoretical foundation for the critical safety analysis of the space nuclear reactor's launch.