摘要
为研究作为双酚A替代物的双酚S(BPS)对金鲫鱼中肾抗氧化指标的影响,将提前驯养适应1周的金鲫鱼随机分为5组,每组10尾鱼.在安全浓度的基础上,设置1个对照组和以等对数浓度差设置1、10、100、1 000μg/L 4个BPS质量浓度组,进行为期15 d的急性暴露.试验结束后分别从每组取3尾鱼进行采样,测定金鲫鱼中肾中总超氧化物歧化酶(T-SOD)、丙二醛(MDA)及过氧化氢酶(CAT)含量,分析不同BPS浓度对于金鲫鱼中肾抗氧化指标的影响.经试验得出,在安全浓度的基础上,随着BPS浓度的升高,金鲫鱼中肾中的CAT活力与总SOD活力显著降低;MDA含量明显增加.
Abstract
To study the effect of bisphenol S(BPS)as a substitute for bisphenol A on renal oxidation indicators in golden crucian carp(Carasslus auratus),golden crucian carp that were domesticated and adapted for one week in advance were randomly divided into 5 groups,with 10 fish in each group.On the basis of safe concentration,one was control group,4 groups were treated with different concentra-tion of BPS(1,10,100,1 000 pg/L,respectively,which are equally spaced in log space)for 15 days.After the test,three fish from each group were taken for sampling,and the contents of total superox-ide dismutase(T-SOD),malondialdehyde(MDA)and catalase(CAT)in the kidney of golden cru-cian carp were measured.The effects of different BPS concentrations on the antioxidant indexes of the kidney of golden crucian carp were analyzed.The results showed that,on the basis of safe concentra-tion,with the increase of BPS concentration,the CAT activity and total SOD activity in the liver of golden crucian carp significantly decreased,while the MDA content significantly increased.
基金项目
现代农业产业技术体系——国家大宗淡水鱼产业技术体系(CARS-45)
NETL
NSTL
万方数据