Effect of dialysate with different sodium ion concentrations on serum sodium and potassium ions in maintenance hemodialysis patients before and after di-alysis
Objective To observe the effects of dialysate sodium concentration(DSC)on ser-um sodium and potassium ions in maintenance hemodialysis patients before and after dialysis.Methods A total of 70 patients undergoing maintenance hemodialysis at the Blood Purification Center of the First Affiliated Hospital of Harbin Medical University from August 2022 to Febru-ary 2023 were selected as the study subjects.They were randomly divided into two groups:the low DSC group(n=38),with a sodium concentration of 137 mmol/L in the dialysis fluid;The sodium concentration in the high DSC group(n=32)was 140 mmol/L;Regular dialysis treat-ment was performed for 3 months.The basic information of two groups of patients and the relat-ed variables of DSC affecting dialysis patients were observed and compared.Results There was no significant difference in age,gender,dialysis age,and dry weight between the two groups of patients(P＞0.05).The serum sodium ion concentration of patients in the low DSC group decreased significantly after the experiment compared to before(P＜0.05),while there was no significant difference in serum sodium ion concentration before and after the experiment in the high DSC group(P＞0.05).There was no significant difference in serum K ions be-tween the two groups of patients after and before the experiment(P＞0.05).The weight gain during the longest dialysis interval before the trial in the low DSC group was significantly lower than that in the high DSC group(P＜0.05).During the treatment,the incidence of hypoten-sion during dialysis was significantly lower in the low DSC group than in the high DSC group(P＜0.05),while there was no significant difference in the incidence of muscle spasms,head-ache,and thirst between the two groups(P＞0.05).Conclusion Compared with high DSC dialysate,low DSC dialysate can significantly reduce the patients'serum sodium level,but it does not have an impact on the patients'serum potassium level.
hemodialysissodium dialysateinterdialysis body weightintradialytic hypoten-sion
NETL
NSTL
万方数据
