Influence of ultrasound-guided nerve block combined with propofol target-controlled infusion on sedative effect and coagulation status in elderly pa-tients undergoing hip joint surgery
Objective To investigate the impact of ultrasound-guided nerve block combined with propofol target-controlled infusion on the sedative effect and coagulation status in elderly patients undergoing hip joint surgery.Methods Ninty elderly patients undergoing hip joint surgery at the Third People's Hospital of Nantong from March 2020 to March 2023 were select-ed.They were divided into combined group and control group using random number table meth-od,with 45 patients in each group.The combined group received anesthesia through ultra-sound-guided lumbosacral plexus nerve block combined with propofol target-controlled infusion,while the control group only received propofol target-controlled infusion.The hemodynamic in-dices[heart rate(HR)and mean arterial pressure(MAP)],sedative effects[Richmond Agita-tion-Sedation Scale(RASS)and bispectral index(BIS)],coagulation indices[thrombin time(TT),prothrombin time(PT),and activated partial thromboplastin time(APTT)],and ad-verse reaction rates of patients in both groups at different time points during the surgery were compared.Results Ten minutes after the injection of anesthetic drugs and during intubation,the HR of the combined group was significantly lower than that of the control group.From 10 mintues after injection of the anesthetic drug to the end of the surgery,the MAP of the com-bined group was consistently lower than that of the control group(P＜0.05).Also,during this period,the RASS and BIS scores of the combined group were lower than those of the control group(P＜0.05).At the end of the surgery,TT,PT and APTT were all higher than before anesthesia,and these indices were notably higher in the combined group than in the control group(P＜0.05).The incidence of intraoperative arrhythmia and postoperative vomiting in the combined group was significantly lower than in the control group(P＜0.05).Conclusion Ultrasound-guided nerve block combined with propofol target-controlled infusion can effectively enhance hemodynamic stability,improve sedation,and maintain a more stable coagulation sta-tus in elderly patients undergoing hip joint surgery.This method enhances patient safety and is worth promoting in clinical practice.
elderly hip joint surgeryultrasound-guided nerve blockpropofol target-con-trolled infusionsedative effectcoagulation status
NETL
NSTL
万方数据
