首页|加速康复外科概念在胸腰椎Denis A型骨折患者围手术期应激反应中的初步应用

加速康复外科概念在胸腰椎Denis A型骨折患者围手术期应激反应中的初步应用

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目的 评估和分析加速康复外科(accelerated rehabilitation surgery,ERAS)概念在胸腰椎Denis A型骨折患者围手术期管理中的应用,并对ERAS对患者生理和心理应激反应的影响进行研究.方法 选取2020 年1 月~2021 年6 月我院手术治疗的60 例Denis A型胸腰椎骨折患者作为研究对象,随机分为常规组和ERAS组,每组 30 例.常规组接受常规围术期管理,ERAS 组在常规组的基础上接受ERAS概念管理.观察和比较两组的治疗效果,以及两组手术前和手术后7d血清皮质醇(cortisol,Cor)和白介素-6(interleukin-6,IL-6)水平,采用焦虑自评量表(Anxiety Self Rating Scale,SAS)评估两组的焦虑状态.结果 通过实施不同的管理模式,ERAS组患者的失血量、术后住院天数和离床活动时间均显著优于常规组(P<0.05);治疗前两组血清Cor和IL-6 水平差异无统计意义(P>0.05);与治疗前比较,两组治疗后7d血清Cor和IL-6 水平升高(P<0.05);ERAS组治疗后7d血清Cor和IL-6 水平低于常规组,差异具有统计学意义(P<0.05);实施前,两组SAS评分无显著差异(P>0.05);实施后,两组患者的SAS评分均下降,ERAS组低于常规组,差异具有统计学意义(P<0.05).结论 ERAS概念应用于胸腰椎Denis A型骨折手术中,可促进患者早期康复,降低血清Cor和IL-6 水平,减轻患者的应激反应,缓解患者焦虑,值得应用和推广.
Preliminary application of the concept of accelerated rehabilitation surgery in perioperative period stress response of patients with Denis A type fractures of the thoracolumbar spine
Objective To evaluate and analyze the application of the concept of accelerated re-habilitation surgery(ERAS)in the perioperative management of patients with Denis A type frac-tures of the thoracolumbar spine and its influence on their physiological and psychological stress response.Methods Sixty patients with Denis A type fractures of the thoracolumbar spine who were admitted to our hospital from January 2020 to June 2021 were selected,they were divided into conventional group and ERAS group according to the random number method,30 cases in each group.Conventional group received conventional perioperative treatment.ERAS group re-ceived the ERAS concept management based on the conventional group.And the healing effect of two groups,serum cortisol(Cor)and interleukin-6(IL-6)before and 7 d after surgery were observed and compared between two groups.Anxiety of two groups was evaluated by Anxiety Self Rating Scale(SAS)score.Results By implementing different management modes,blood loss,postoperative hospital days and time out of bed were better in the ERAS group than in the conventional group,with statistically significant differences(P<0.05).There was no signifi-cant difference in serum Cor and IL-6 levels between the two groups before treatment(P>0.05).Serum levels of Cor and IL-6 in both groups were increased at 7 d after surgery(P<0.05).Serum levels of Cor and IL-6 in the ERAS group were lower seven days after surgery than in the conventional group,with statistical significance(P<0.05).Before treatment,there was no significant difference in SAS score between two groups(P>0.05);After treat-ment,SAS scores were decreased in both groups and ERAS group was lower than the conven-tional group,the difference was statistically significant(P<0.05).Conclusion The applica-tion of the ERAS concept in the operation of Denis type A fractures of the thoracolumbar spine can promote the early recovery of patients,reduce the level of serum Cor and IL-6,reduce the stress response and reduce the anxiety of patients,which is worthy of promotion and applica-tion.

accelerated rehabilitation surgery conceptDenis type A fractures of the thoraco-lumbar spineperioperative periodstress response

袁之木、刘建民、邱燕森、孙文建

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东南大学医学院附属南京同仁医院 骨科,江苏 南京 211102

加速康复外科概念 Denis胸腰椎A型骨折 围手术期 应激反应

江苏省自然科学基金江苏省南京市卫生医学发展专项

2019SC0815YKK21247

2024

哈尔滨医科大学学报
哈尔滨医科大学

哈尔滨医科大学学报

CSTPCD
影响因子:1.117
ISSN:1000-1905
年,卷(期):2024.58(2)
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