Preliminary application of the concept of accelerated rehabilitation surgery in perioperative period stress response of patients with Denis A type fractures of the thoracolumbar spine
Objective To evaluate and analyze the application of the concept of accelerated re-habilitation surgery(ERAS)in the perioperative management of patients with Denis A type frac-tures of the thoracolumbar spine and its influence on their physiological and psychological stress response.Methods Sixty patients with Denis A type fractures of the thoracolumbar spine who were admitted to our hospital from January 2020 to June 2021 were selected,they were divided into conventional group and ERAS group according to the random number method,30 cases in each group.Conventional group received conventional perioperative treatment.ERAS group re-ceived the ERAS concept management based on the conventional group.And the healing effect of two groups,serum cortisol(Cor)and interleukin-6(IL-6)before and 7 d after surgery were observed and compared between two groups.Anxiety of two groups was evaluated by Anxiety Self Rating Scale(SAS)score.Results By implementing different management modes,blood loss,postoperative hospital days and time out of bed were better in the ERAS group than in the conventional group,with statistically significant differences(P<0.05).There was no signifi-cant difference in serum Cor and IL-6 levels between the two groups before treatment(P>0.05).Serum levels of Cor and IL-6 in both groups were increased at 7 d after surgery(P<0.05).Serum levels of Cor and IL-6 in the ERAS group were lower seven days after surgery than in the conventional group,with statistical significance(P<0.05).Before treatment,there was no significant difference in SAS score between two groups(P>0.05);After treat-ment,SAS scores were decreased in both groups and ERAS group was lower than the conven-tional group,the difference was statistically significant(P<0.05).Conclusion The applica-tion of the ERAS concept in the operation of Denis type A fractures of the thoracolumbar spine can promote the early recovery of patients,reduce the level of serum Cor and IL-6,reduce the stress response and reduce the anxiety of patients,which is worthy of promotion and applica-tion.
accelerated rehabilitation surgery conceptDenis type A fractures of the thoraco-lumbar spineperioperative periodstress response