Application of ultrasonic shear wave elastography in assessing clinical staging of fibrosis in patients with hepatitis B
Objective To investigate the application value of ultrasonic shear wave elastogra-phy in evaluating the clinical staging of patients with chronic hepatitis B fibrosis.Methods Sixty-two patients with chronic hepatitis B who were admitted to Heilongjiang Provincial Hospi-tal from January 2020 to January 2022 were selected for ultrasonic shear wave elastography and liver biochemical tests,respectively.The pathological results of needle biopsy were compared and analyzed.Results The pathological results showed that among the 62 patients participat-ing,there were 10 patients in S1 stage,30 patients in S2 stage,and 22 patients in S3 stage;There were significant differences in the elastic modulus values among patients in stage three,and its elastic modulus value gradually increased with the severity of liver fibrosis,and the difference was statistically significant(P<0.05);The elastic modulus value of patients with chronic hepatitis B fibrosis and its pathological stage(r=0.562,P<0.05),and its serologi-cal indexes total bilirubin(TBil),alanine aminotransferase(ALT)and aspartate aminotrans-ferase(AST)values were significantly positively correlated(P<0.05).Conclusion Ultra-sonic shear wave elastography can accurately and quantitatively evaluate the clinical stage of fi-brosis in patients with chronic hepatitis B on the basis of non-invasive examination.
ultrasound imagingelastographyhepatitis Bliver fibrosisliver biopsy
NETL
NSTL
万方数据
