Analysis of 15 autosomal STR among Xinjiang Kazaks and the inference of genetic relationship among 40 Chinese populations based on the 15 STRs
Aim: To investigate the population genetic data of Xinjiang Kazaks and to analyze the genetic distance and genetic relationship among 40 Chinese populations including Kazaks.Methods: The 15 autosomal STR loci in Xinjiang Kazaks samples were analyzed;corresponding frequency data of 15 STR loci of other Chinese populations was collected from published literatures.The genetic distance(Rst) among the 40 populations was calculated by Phylip 3.69 and Arlequin 3.5, and the phylogenetic tree was constructed with Neighbor-Joining method.Results: All the other 14 STRs except TPOX had high He and PIC values more than 0.7 in Xinjiang Kazaks.The mean Rst among the 40 populations was 0.055 1, the mean Rst was 0.044 9 among the 18 Han populations, and the mean Rst was 0.057 6 among the other 22 minorities.In the tree graph, the Han nationality displayed a lot of branches, showing a trend of more and more diversity;some of the minorities gathered together although they were geographically distant.Conclusion: The 15 autosomal STR are highly polymorphic in Xinjiang Kazaks and the 15 STR frequency data published by the forensic science community can be conveniently used for the study of human evolution, ethnic origin and ethnic group relationships.
forensic medicineautosomeSTRgenetic distanceChinese population
国家科技期刊平台
NSTL
万方数据
维普
