目的:对比分析小球囊预扩张治疗布加综合征(BCS)合并混合性下腔静脉血栓(IVCT)一期和分期治疗方案的疗效和成本效益.方法:回顾性收集2011 年1 月至2020 年12 月郑州大学第一附属医院收治的BCS合并混合性IVCT、行小球囊预扩张治疗的患者116 例,其中,一期治疗方案49 例,分期治疗方案 67 例.对比分析两种治疗方案的血栓溶解率、技术成功率、住院时间、住院费用、医保补偿率.结果:两种治疗方案中位总住院时间(22.0 d vs 22.5 d,P =0.303)和医保补偿率(58.92%vs 55.75%,P =0.965)差异无统计学意义,而一期治疗方案血栓溶解率(100.0%vs 87.5%,P =0.012)、技术成功率(100.0%vs 62.7%,P =0.001)和中位人均住院费用(45 676.51元 vs 61 283.21 元,P<0.001)均优于分期治疗方案.结论:一期治疗方案具有更高的溶栓效率和技术成功率,以及更低的住院费用,应被临床优先选择.
Comparative analysis of the efficacy and cost-effectiveness of single-stage and two-stage treatment strategy using small-diameter balloon pre-dilation for Budd-Chiari syndrome complicated by mixed inferior vena cava thrombosis
Aim:To compare the efficacy and cost-effectiveness of single-stage and two-stage treatment strategy using small-diameter balloon pre-dilation for Budd-Chiari syndrome(BCS)complicated by mixed inferior vena cava thrombosis(IVCT).Methods:From January 2011 to December 2020,116 patients with BCS complicated by mixed IVCT who under-went small-diameter balloon pre-dilation at the First Affiliated Hospital of Zhengzhou University were included in this retro-spective study.Out of them,49 patients underwent single-stage treatment strategy while 67 underwent two-stage treatment strategy.The differences of thrombolysis rate,technical success rate,hospital stay,insurance reimbursement rate,and hospi-talization cost were analyzed between the 2 groups.Results:There were no significant differences between the 2 groups in median hospital stay(22.0 days vs 22.5 days,P =0.303)or insurance reimbursement rate(58.92%vs 55.75%,P = 0.965).However,the single-stage group exhibited significantly higher thrombolysis rate(100.0%vs 87.5%,P =0.012),technical success rate(100.0%vs 62.7%,P = 0.001),and median per capita hospitalization cost(45 676.51 CNY vs 61 283.21 CNY,P<0.001)compared with the two-stage group.Conclusion:In comparison with two-stage treatment strat-egy,single-stage treatment strategy exhibits higher thrombolytic efficiency and technical success rate,and lower hospitaliza-tion costs,and thus should be given clinical priority.
万方数据
维普
