郑州大学学报(医学版)2024,Vol.59Issue(1) :133-135.DOI:10.13705/j.issn.1671-6825.2023.03.050

术后24h内血清降钙素原水平对肺移植术后短期结局的预测价值

Predictive value of serum procalcitonin level within 24 hours after opera-tion for short-term outcomes of lung transplantation

王慧敏 王鑫 赵丽丽 朱金霞 李晓莉 冯敏 郭铁
郑州大学学报(医学版)2024,Vol.59Issue(1) :133-135.DOI:10.13705/j.issn.1671-6825.2023.03.050

术后24h内血清降钙素原水平对肺移植术后短期结局的预测价值

Predictive value of serum procalcitonin level within 24 hours after opera-tion for short-term outcomes of lung transplantation

王慧敏 1王鑫 1赵丽丽 1朱金霞 1李晓莉 1冯敏 1郭铁1
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作者信息

  • 1. 郑州大学第一附属医院外科重症监护室 郑州 450052
  • 折叠

摘要

目的:探讨术后24h内血清降钙素原(PCT)水平对肺移植术后短期结局的预测价值.方法:回顾性分析2021 年1 月至2022 年6 月于郑州大学第一附属医院行肺移植术患者的资料,检测术后24h内血清PCT水平.术后6 个月内死亡30 例,存活49 例.结果:死亡组术后24h内血清PCT水平1.330(0.384,7.225)ng/mL高于存活组0.430(0.135,1.185)ng/mL(P<0.05).Logistic回归分析结果显示,术后24h内血清PCT水平升高的肺移植患者术后6 个月内死亡风险增加,OR(95%CI)为1.416(1.126~1.781).术后24h内血清PCT水平预测肺移植术后6 个月内死亡的ROC曲线,AUC(95%CI)为0.711(0.587~0.835).结论:术后24h内血清PCT水平对肺移植术后短期结局具有一定的预测价值.

Abstract

Aim:To explore the predictive value of serum PCT level within 24 hours after operation for short-term out-comes of lung transplantation.Methods:Data of patients underwent lung transplantation in the First Affiliated Hospital of Zhengzhou University from January 2021 to June 2022 were retrospectively analyzed.Serum PCT level within 24 hours after operation was detected.During 6 months after operation,30 cases died,49 cases were survival.Results:The serum PCT lev-el within 24 hours after operation were 1.330(0.384,7.225)ng/mL in the death group and 0.430(0.135,1.185)ng/mL in the survival group,and the difference was significant(P<0.05).Logistic regression analysis results showed that the short-term death risk of lung transplantation patients elevated with the increase of serum PCT level,and OR(95%CI)was 1.416(1.126-1.781).AUC(95%CI)of ROC curve of serum PCT level within 24 hours after operation to predict short-term death was 0.711(0.587-0.835).Conclusion:Serum PCT level within 24 hours after operation maybe have predic-tive value for the outcomes within 6 months after lung transplantation.

关键词

肺移植/降钙素原/短期结局

Key words

lung transplantation/procalcitonin/short-term outcome

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出版年

2024
郑州大学学报(医学版)
郑州大学

郑州大学学报(医学版)

CSTPCD北大核心
影响因子:1.246
ISSN:1671-6825
参考文献量1
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