Application and dosimetric analysis of brachytherapy with free hand im-plantation for cervical cancer guided by multimodal imaging technology
Aim:To explore the application and dosimetry of brachytherapy for cervical cancer with free hand implanta-tion guided by multimodal imaging technology.Methods:A total of 98 patients with cervical cancer were selected,and were allocated into study group(49 cases)and control group(49 cases).The control group was treated with CT image guided brachytherapy with intertissue free hand implantation.The study group conducted real-time ultrasound combined with CT im-age guided brachytherapy with intertissue free hand implantation.The implantation characteristics,efficacy,90%high risk clinical target volume dose(HR-CTVD90),cumulative doses of organ at risk and complications between the 2 groups were compared.Results:The time of single needle insertion in the study group was shorter than that in the control group(P<0.001).The efficacy of the study group at 3 and 6 months after brachytherapy was better than that of the control group(P<0.05).Tumor size of 5 to<6 cm HR-CTVD90 and6 to<7 cm HR-CTVD90 in the study group were higher than those in the control group(P<0.05).Bladder,sigmoid and rectal cumulative doses in the study group were lower than those in the control group(P<0.05).The total complication rate of the study group was lower than that of the control group(P = 0.036).Conclusion:Brachytherapy guided by multimodal imaging technology has good clinical efficacy,could effectively reduce the time of single needle insertion and the risk of complications and has dosimetry advantages.
multimodal imaging technologycervical cancerfree hand implantationbrachytherapydosimetry
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