Clinical analysis of cytomegalovirus pneumonia after allogeneic hemato-poietic stem cell transplantation
Aim:To analyze the clinical characteristics of cytomegalovirus(CMV)pneumonia after allogeneic hemato-poietic stem cell transplantation(allo-HSCT).Methods:Clinical features and laboratory data of 29 patients with CMV pneu-monia after allo-HSCT from January 1,2019 to October 31,2022 at the First Affiliated Hospital of Zhengzhou University were collected.Results:Among the 29 patients,1 case with confirmed diagnosis,16 cases with clinical diagnosis,and 12 ca-ses with suspected diagnosis;18(62.1%)were effective and 11(37.9%)were ineffective after treatment.The proportion of the patients with other pathogenic microorganism infection(P =0.001),graft-versus-host disease(P =0.005),and invasive ventilation(P =0.018)in ineffective group were higher than those in effective group.Conclusion:It's difficult to diagnose definitely and treat CMV pneumonia after allo-HSCT.It's necessary to clarify the diagnosis as soon as possible,so to receive effective treatment earlier.
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