Influencing factors of metabolic syndrome in patients with schizophrenia and intervention effect of pharmacist-led team management
Aim:To investigate the influencing factors of metabolic syndrome(MS)in patients with schizophrenia and the effectiveness of pharmacist-led team management application.Methods:Eighty cases of schizophrenia with MS who visi-ted the hospital from April 2022 to September 2022 were selected(MS group),and 80 cases of schizophrenia without MS who visited the hospital during the same period were selected as control,and the influencing factors of MS were analyzed by Logistic regression.The patients in the MS group were randomly allocated into the intervention group and control group ac-cording to the random number ranking method,and both had 40 cases.The patients in control group was given conventional nursing intervention,and the patients in the intervention group were given pharmacist-led team management on basis of con-trol group,both for 6 months.The differences in metabolic indexes(BMI,waist circumference,fasting glucose,high-density cholesterol,triglycerides),mental status[negative/positive symptom scale and general psychopathology scale],and quality of survival[World Health Organization Quality of Living Scale(WHOQOL-BREF)]were compared between the 2 groups be-fore and after the intervention.Results:Logistic regression analysis showed that elder age,smoking,high IL-6 level,4G/4G+4G/5G of PAI-1 gene,and hyperlipidemia were risk factors for MS,and appropriate exercise habit was protective factor(P<0.05).The differences in BMI,waist circumference,fasting glucose,triglycerides,general psychopathology scale,psychological functioning,and physical health scores before and after the intervention were higher in the intervention group than those in control group(P<0.05).Conclusion:The application of pharmacist-led team management in cases of schizophrenia with MS can effectively improve metabolic indicators,relieve clinical symptoms,and improve quality of survival.
schizophreniametabolic syndromeinfluencing factorled by pharmacistteam managementintervention effect
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