Analysis of predictive factors for anti-epilepsy drug resistance in patients with post-stroke epilepsy
Aim:To explore the predictive factors for anti-epilepsy drug resistance in patients with post-stroke epilepsy(PSE).Methods:A total of 141 patients with PSE who were admitted from January 2017 to January 2021 were collected,and were allocated into drug resistance group(n=23)and non-drug resistance group(n=118)according to the definition of anti-epilepsy drug resistance by the International League Against Epilepsy.Logistic regression analysis was used to deter-mine the influential factors for anti-epilepsy drug resistance and the predicting value of those factors was assessed.Results:Logistic regression analysis showed that first stroke age≤50 years,hemorrhagic stroke,and medium and severe stroke were risk factors of anti-epilepsy drug-resistance[(OR(95％CI)was 1.226(1.108-1.356),6.866(1.197-39.390),0.073(0.013-0.417)].First stroke age≤50 years and hemorrhagic stroke had higher predictive value for anti-epilepsy drug re-sistance,the sensitivity was 0.826 and 0.739,and the specificity was 0.848 and 0.780.Conclusion:First stroke age ≤50 years and hemorrhagic stroke have high predictive value for anti-epilepsy drug resistance in the patients with PSE.
anti-epilepsy drug resistancefirst stroke ageNIHSS scorehemorrhagic strokepost-stroke epilepsy
万方数据
维普
