Association of oxidative balance score with all-cause death and cardiovas-cular event death in patients with asthma:a NHANES data analysis
Aim:To explore the association of oxidative balance score(OBS)with all-cause death and cardiovascular event death in patients with asthma.Methods:Data from the National Health and Nutrition Examination Survey(NHANES)from 1999 to 2018 were used in this study.Sixteen dietary factors and 4 lifestyle factors were selected for OBS scoring,and the enrolled asthma patients were allocated into 3 groups(Q1,Q2,Q3 groups)according to the tertiles of OBS.Cox regres-sion analysis was employed to investigate the association between OBS and all-cause death as well as cardiovascular event death in the asthmatic population.Subgroup analysis and interaction tests were used to examine whether this association was stable in different populations.Results:This study included 6 739 participants.Cox regression analysis showed that after ad-justing confounding factors,individuals in Q2 and Q3 groups had lower risk of all-cause death(HR=0.65,95%CI:0.49-0.86;HR=0.53,95%CI:0.37-0.77),and those in Q3 group had lower risk of cardiovascular event death(HR=0.45,95%CI:0.27-0.76).Subgroup analysis and interaction tests indicated that gender,chronic obstructive pulmonary disease,hypertension,coronary artery disease,stroke,or diabetes had no significant interactions between OBS and all-cause death(P>0.05).Conclusion:High OBS is a protective factor against all-cause death and cardiovascular event death in the asthmatic population.
万方数据
维普
