首页|131I SPECT/CT在甲状腺癌术后随访中的应用价值

131I SPECT/CT在甲状腺癌术后随访中的应用价值

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目的:探究131I单光子发射CT/CT(SPECT/CT)在甲状腺癌术后随访中的应用价值.方法:选取2018 年3 月至2020 年5 月行全切术的分化型甲状腺癌患者122 例,术后接受131I治疗3d,然后行131I全身显像(131I-WBS)和SPECT/CT,术后随访1a,记录患者临床再分期、术后复发及转移情况.结果:术后临床再分期131I-WBS判断正确率为75.4%(92/122),131I SPECT/CT为91.8%(112/122),131I SPECT/CT判断正确率高于131I-WBS(P<0.001).术后随访1 a,12 例复发.131I SPECT/CT高危显像对术后复发的检出率为12/12,高于131I-WBS的7/12(P<0.001).122 例共526 处131I阳性摄取,其中 347 处转移.131I SPECT/CT对转移灶诊断敏感度(98.6%vs 62.0%)、特异度(98.9%vs 85.5%)均高于131I-WBS(P<0.001).结论:131I SPECT/CT可为甲状腺癌术后临床再分期及复发危险度分层提供更多准确信息,对转移灶具有较高的判断价值.
Application value of 131I SPECT/CT in postoperative follow-up of thyroid cancer
Aim:To explore the application value of 131 I single-photon emission CT/CT(SPECT/CT)in postoperative follow-up of thyroid cancer.Methods:A total of 122 patients with differentiated thyroid cancer undergoing total resection between March 2018 and May 2020 were enrolled as the research objects,and all were treated with 131 I for 3 days after oper-ation and then underwent 131 I whole-body scan(131 I-WBS)and SPECT/CT.All were followed up for 1 year,and the clinical restage,postoperative recurrence and metastasis were recorded.Results:In terms of postoperative clinical restaging,accura-cy rate of 131 I SPECT/CT was higher than that of 131 I-WBS[91.8%(112/122)vs 75.4%(92/122),P<0.001].Twelve cases relapsed.Detection rate of postoperative recurrence by 131 I SPECT/CT was higher than that by 131 I-WBS(12/12 vs 7/12,P<0.001).In the122 patients,there were526 131 Iuptakingloci,inwhich347 weremetastaseslesions.Thesensitivity(98.6%vs 62.0%),specificity(98.9%vs 85.5%)of 131 I SPECT/CT were significantly higher than those of 131 I-WBS for the diagnosis of metastases(P<0.001).Conclusion:131 I SPECT/CT can provide more accurate information for postopera-tive clinical restaging and recurrence risk stratification of thyroid cancer,and has high diagnostic value for metastasis.

131 I SPECT/CTthyroid cancerpostoperative follow-up

何清、史育红、王朝点

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成都医学院第二附属医院·核工业四一六医院核医学科 成都 610051

131I SPECT/CT 甲状腺癌 术后随访

四川省医学科研课题计划项目

S18001

2024

郑州大学学报(医学版)
郑州大学

郑州大学学报(医学版)

CSTPCD北大核心
影响因子:1.246
ISSN:1671-6825
年,卷(期):2024.59(5)