首页|八宝丹胶囊预防导尿管相关性尿路感染的效果

八宝丹胶囊预防导尿管相关性尿路感染的效果

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目的:探讨八宝丹胶囊预防导尿管相关性尿路感染(CAUTI)的效果.方法:选择2022 年6 月至2023 年2 月于郑州大学第一附属医院泌尿外科就诊且留置导尿管的患者.根据治疗方案分为3 组,留置导尿管后静脉给予抗生素(拉氧头孢钠)者为对照组(n=73),给予八宝丹胶囊者为试验组A(n=72),给予八宝丹胶囊联合抗生素者为试验组B(n=72).在留置导尿管第3、5、7 天及拔除导尿管48h行尿常规、尿培养检查,比较各组总CAUTI发生率、膀胱过度活动症(OAB)发生率及不良反应发生率.结果:对照组、试验组A、试验组B总CAUTI发生率分别为39.7%、36.1%、20.8%,OAB发生率分别为30.1%、18.1%、11.1%,试验组B总CAUTI发生率、OAB发生率低于对照组(P<0.017).3 组治疗期间均未发生不良反应.结论:八宝丹胶囊联合抗生素使用可有效预防CAUTI发生,并且具有良好的安全性.
Efficacy of Babaodan capsules in preventing catheter-associated urinary tract infection
Aim:To investigate the clinical effectiveness of Babaodan capsules in prevention of catheter-associated uri-nary tract infection(CAUTI).Methods:The patients with indwelling urinary catheters who were admitted to the Department of Urology of the First Affiliated Hospital of Zhengzhou University from June 2022 to February 2023 were selected and allo-cated into 3 groups according to the treatment;those who received standard antibiotic treatment after catheterization were control group(n=73),and those treated with Babaodan capsules,a combination of Babaodan capsules and antibiotics were named as trial group A(n=72)and trial group B(n=72),respectively.On the 3rd,5th and 7th day after catheterization,and 48 hours after catheter removal,urine routine and culture tests were conducted.The incidences of CAUTI,overactive bladder(OAB)and adverse reactions was compared among the 3 groups.Results:The incidence of total CAUTI in control group,trial group A and trial group B was 39.7%,36.1%and 20.8%,while the incidence of OAB was 30.1%,18.1%and11.1%,respectively.The incidences of CAUTI and OAB in trial group B were lower than those in the other2 groups(P<0.017).No adverse reactions occurred during the treatment in all3 groups.Conclusion:Babaodan capsules in combi-nation with antibiotics are effective in preventing CAUTI and have favourable safety.

urinary tract infectioncatheterBabaodan capsuleprevention

高远、袁志浩、王永鑫、辛文成、乔保平

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郑州大学第一附属医院泌尿外科 郑州 450052

尿路感染 导尿管 八宝丹胶囊 预防

河南省教育厅基金资助项目

202102310447

2024

郑州大学学报(医学版)
郑州大学

郑州大学学报(医学版)

CSTPCD北大核心
影响因子:1.246
ISSN:1671-6825
年,卷(期):2024.59(5)