Clinical efficacy of orthodontics combined with periodontal treatment on malocclusion with periodontitis
Aim:To explore clinical efficacy of orthodontics combined with periodontal treatment on malocclusion with periodontitis.Methods:A total of 98 patients with malocclusion and periodontitis were selected as research subjects,and allo-cated into observation group and control group with 49 cases in each group according to random number ranking method.Con-trol group received simple periodontal treatment,and the observation group was given combined orthodontics-periodontal treat-ment.Before and after treatment,comparisons were performed on periodontal clinical indexes[probing depth(PD),gingival in-dex(GI),plaque index(PLI),sulcus bleeding index(SBI),clinical attachment loss(CAL)],periodontal pathogenic bacteria[aggregatibacter actinomycetemcomitans(A.a),porphyromonas gingivalis(P.g),fusobacterium nucleatum(F.n)],levels of periodontal inflammatory factors(CRP,TNF-α,IL-4,IL-6),gingival crevicular fluid bone metabolism indicators[bone gla-pro-tein(BGP),procollagenⅠtype N-terminal peptide(PⅠNP),C-telopeptide of typeⅠprocollagen(CTX-Ⅰ),procalcitonin(PCT)]and clinical efficacy,complications.Results:The total effective rate of the observation group was higher than that of control group(93.88%vs 79.59%,P=0.037).After treatment,the change degree of PD,GI,SBI,PLI,CAL,A.a,P.g and F.n,levels of CRP,TNF-α,IL-4 and IL-6,and the levels of BGP,PⅠNP,CTX-Ⅰand PCT in gingival crevicular fluid in the ob-servation group were larger than those in control group(P<0.05).There were no significant differences in complications between the 2 groups(P=0.268).Conclusion:Orthodontics combined with periodontal treatment has a prominent clinical efficacy on malocclusion with periodontitis with few postoperative complications.
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