Taking a flotation feeding coal(ZF coal)in Shanxi Province as the test coal sample,the opti-mization of coal flotation desulfurization and ash reduction process conditions was studied by the Box-Behnken response surface methodology(RSM)using non-ionic surfactant Span20 emulsified kerosene as the collector.The dosages of collector,foaming agent and inhibitor were selected as three main in-fluencing factors.The software Design Expert 8.0.6 was used to analyze and calculate the test data,and the regression equations between the desulfurization rate,deashing rate,flotation perfection and the three influencing factors were obtained by fitting.The optimum flotation process conditions are as follows:collector dosage of 300 g/t,foaming agent dosage of 116 g/t and inhibitor dosage of 123 g/t.Under these process conditions,the theoretical flotation desulfurization rate is 9.45%,deashing rate is 28.51%and flotation perfection is 17.54%.The experimental results are consistent with the theo-retical values,indicating that the model is effective and the optimization scheme is credible.