Preparation and Antibacterial Properties of Unsteady High Activity Composite Zinc Oxide Powder
A gel heat treatment process was designed to prepare unstable and highly active nano-zinc oxide(UHA-NanoZnO)antibacterial powder.A composite antibacterial coating was prepared on the surface of medical stainless steel using polylactic acid(PLA)as the base material,UHA-NanoZnO as the antibacterial active substance and methylene chloride as the solvent.The microstructure was char-acterized by XRD,SEM and HRTEM,and the release rate of zinc ions was measured by ICP.XRD re-sults show that the prepared UHA-NanoZnO has an incomplete crystalline structure.The SEM results show that the microstructure is monodisperse spherical.It has good dispersion;HRTEM results show that the edge of UHA-NanoZnO particles is amorphous.ICP results show that the zinc ion release rate is higher than that of 20 nm high crystalline Nano-Zno.Compared with completely crystalline nano-zno,UHA-NanoZnO showed better antibacterial performance and faster release rate of active sub-stance.The minimum inhibitory concentration(MIC)for E.coli was 0.125 g/L,while the minimum in-hibitory concentration(MIC)for zinc oxide with particle size of 20 nm was 0.250 g/L.The antibacteri-al rate of the composite coating against E.coli reached 99.9%.
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