Dynamics Analysis and Model Construction in Fabrication of Chinese Medicine Sustained Release Dropping Pill
Chinese medicine is one of the cherished fields in China.Dropping pill is an important fabrication form in Chinese medicine formulations,and has attracted increasing attention of pharmaceutical companies and researchers.In this paper,the dripping fabrication process of Chinese medicine sustained release dropping pill was exploded through numerical method.The dynamic mechanism of dripping and solidifying process was analyzed.The influences of the liquid rheological properties,the type and temperature of the forming medium,and the temperature and thickness of the wall material on key indicators such as sphericity and eccentricity of the dropping pills were studied,providing theoretical basis and experimental support for the industrial fabrication of high-quality dropping pills.The results indicated that the density and viscosity of the forming medium have an impact on its relative velocity with the dropping pill.Regularity of the dropping pill improves with the decrease of relative velocity value.The eccentricity of dropping pill is significantly affected by the solidification time of the wall material.Adjusting the dripping parameters and controlling the solidification time can reduce the eccentricity.
NETL
NSTL
万方数据
维普
