This paper investigates the performance optimization of flue gas denitrification catalysts and their resistance to SO2 poisoning.By constructing a micro-reactor fixed-bed reaction system,precise reaction evaluations of the catalysts were conducted,and an advanced flue gas analyzer was utilized to conduct detailed analysis of the post-reaction gas composition.The research focuses on the impact of introducing Cu and Ce species on the denitrification efficiency of the catalysts,revealing that their incorporation not only significantly enhances the efficiency of the denitrification reaction but also improves the stability of the catalysts under SO2-laden conditions,effectively resisting SO2 poisoning.This study provides theoretical guidance for the development of reliable flue gas denitrification catalysts and holds significant implications for advancing the technology of flue gas denitrification.