In situ product removal used in 2-phenylethanol production by microbial conversion
2-phenylethanol（2-PEA）is an aromatic alcohol with rose fragrance,which has been widely used as an essence component in fine chemical and food industries.Compared with the low quality 2-PEA by chemical synthesis and the low yield and high price 2-PEA by plant extraction,2-PEA production by microbial conversion has been increasingly valued,but the product inhibition of 2-PEA to microbes is a problem.In situ product removal（ISPR）techniques can effectively improve 2-PEA yield by reducing product inhibition.The progress of ISPR techniques used in 2-PEA production by microbial conversion was introduced including the extraction,adsorption and membrane-based pervaporation and penetration extraction.The combination of ISPR techniques,high-efficient fermentation process and strain screening for high yield,the development of relatively simple instruments and post-processing techniques are suggested to be the research focus,so as to significantly improve the yield of 2-PEA and realize the industrialization of 2-PEA production by microbial conversion.
国家科技期刊平台
NSTL
万方数据
维普
